Attended Oxford High School GDST.
In the Independent on Sunday [UK] 2006 Pink List - a list of the most influential gay men and women - Margolyes came no. 93, down from last year's no. 29.
Is of Belarussian-Jewish descent.
She was awarded O.B.E. (Officer of the Order of the British Empire) in the 2002 Queen's New Years Honours List for her services to drama.
Works and has homes in the US, UK and Australia.