Author of science fiction and nonfiction. His novel Flowers for Algernon has never gone out of print.
The Milligan Wars, a continuation of The Minds of Billy Milligan, has never been published the United States.
The short story version of "Flowers for Algernon" won the Hugo Award in 1960. The novel version won the Nebula Award in 1966. (It tied with Samuel R. Delany's novel Babel-17 for the Nebula Award.) Keyes also won a Special Author Emeritus award in 1999.
Was on the English faculty at Ohio University until he moved to Florida.