Best remembered for his direction of Charley Chase, Stan Laurel and Oliver Hardy comedies for Hal Roach, Horne helmed a single "Our Gang" feature, When the Wind Blows (1930). One of the children in the cast would have been Horne's son-in-law, had he lived: In 1944, two years after his death, Horne's daughter June Horne married Jackie Cooper.
Director of "Big Business" (1929), one of the first 100 films selected by the Library of Congress for the National Film Registry.
Father of Victoria Horne (1911-2003).
Father of actor, James Wesley Horne Jr. (1917-2009).
Great-uncle of George Stevens Jr..
Nephew of actress Georgia Woodthorpe.
Twin children: June Horne and James Jr. (b. 28 March 1917).
Uncle of director George Stevens and cameraman Jack Stevens.