The bridge where the doctor observes a woman jumping, is actually the Colorado Street Bridge in Pasadena, California. In the early twentieth century, it was known among local residents as a suicide bridge.
The character Mrs. William Carlo was originally called Mrs. William Brandt, but a New York socialite of the same name objected to it's use, so all references were changed right before the premier.
The movie was banned in Pennsylvania on the grounds it would tend to corrupt morals. The National Board of Review passed the film for adults only.
The trial of the doctor in the film for sending birth control booklets through the mails paralleled the Margaret Sanger case in 1915, when she was tried for the same reason.
Universal's most successful film released in 1916.