A follow-up, "The Spider Woman Strikes Back" (1946) , has no relation to the HOLMES feature, as Gale Sondergaard plays a completely different character.
References five original Sir Arthur Conan Doyle Sherlock Holmes short stories and novels.
- The death of Sherlock Holmes from 'The Adventure of the Final Problem'.
- A bust of Sherlock Holmes from The Adventure of the Empty House.
- A poisonous creature enters a room through an air shaft from The Adventure of the Speckled Band.
- The murderous pygmy and the footprint of a child from The Sign of Four
- And a poisonous substance burnt in a fire from The Adventure of the Devil's Foot.
Shooting lasted from May 10-early June, 1943, released January 21, 1944 (copyright 1943) .
The scene in which a spider enters Holmes's room through the radiator is inspired by a similar scene in the story 'The Adventure of the Speckled Band'.
The seventh of fourteen films based on Arthur Conan Doyle's fictional consulting detective Sherlock Holmes starring Basil Rathbone as Sherlock Holmes and Nigel Bruce as Doctor Watson.