Her role as Queen Omphale was the most widely seen one for French-born model-turned-actress Sylvia Lopez. At the time she filmed this she had leukemia. She was only able to complete one more film and died in November while working on a second.
His role as Antaeus, who dwarfs even Steve Reeves, was the final film appearance for former world heavyweight boxing champion Primo Carnera.
The score for this contains themes from its predecessor, Le fatiche di Ercole. They became the most famous compositions, internationally, for composer Enzo Masetti. Masetti retired after completing the score for this film.