Zona Gale re-wrote her novel into a play, which was first produced by Brock Pemberton at the Belmont Theater, New York. The premier took place on 27 December, 1921. The following cast was featured: Carroll McComas as Lulu Bett, William Holden as Dwight Deacon, Catherine Doucet as Ina Deacon (billed as Catherine Calhoun Doucet), Jack Lionel Bohn as Bobby Larkin (billed as Jack Bohn), Willard Robertson as Neil Cornish, Louise Closser Hale as Miss Bett (misspelled as Louis Closser Hale), and Brigham Royce as Ninian Deacon, plus Lois Shore as Manona Deacon and Beth Varden as Diana Deacon.
The original Broadway production of "Miss Lulu Bett" by Zona Gale opened on December 27, 1920 at the Belmont Theater, ran for 198 performances and won the Pulitzer Prize in Drama in 1921.