Judy Geeson and Lulu were both reunited with Sidney Poitier in the TV sequel To Sir, with Love II directed by Peter Bogdanovich
Avis Bunnage had a small role that was removed in editing.
The band at the dance, The Mindbenders, were the original backing band for Wayne Fontana. Wayne Fontana and the Mindbenders had a hit with "Game of Love" while the Mindbenders had a hit with "Groovy Kind of Love". Eric Stewart from the Mindbenders went onto greater success as part of 10CC.
The film did so unexpectedly well in America that Columbia Pictures did market research to find out why so many people had gone to it. Their answer: Sidney Poitier.
The film was held from release for more than a year until Columbia Pictures decided to open it in Westwood, California in the summer of 1967 where it really broke through.
The first movie role for Michael Des Barres.
The first movie role for Patricia Routledge.
The London bus that appears in several sequences at the start of the film, LLU 829, and in some later sequences, still survives today as a preserved vintage vehicle, and can be seen at the East Anglia Transport Museum, Carlton Colville, Lowestoft, England.
The South African Publications Control Board banned this film, claiming that it was "offensive to see a Black male teaching a class of white children".