In 1973 he was awarded the Gold Medal from the National Football Foundation for his days playing football for Glendale High School and USC.
In 1973 he was honored with the Veterans of Foreign Wars highest award - The National Americanism Gold Medal.
In 1974, with the Vietnam war still continuing, The Harvard Lampoon invited Wayne to The Harvard Square Theater to award him the "Brass Balls Award" for his "Outstanding machismo and a penchant for punching people". Wayne accepted and arrived riding atop an armored personnel carrier manned by the "Black Knights" of Troop D, Fifth Regiment. Wayne took the stage and ad-libbed his way through a series of derogatory questions with adroitness, displaying an agile wit that completely won over the audience of students.
In 1975, for the first time since his arrival in Hollywood 47 years earlier, he did not act in any movies. Production began in January of the following year for his last, The Shootist (1976).
In 1978, after recovering from open heart surgery, he had a script commissioned for a film called "Beau John" in which he would star with Ron Howard, but due to his declining health it never happened.
In 1979, as it became known that Wayne was dying of cancer, Barry Goldwater introduced legislation to award him the Congressional Gold Medal. Maureen O'Hara and Elizabeth Taylor flew to Washington to give testimony, and signed statements in support of the motion from Frank Sinatra, Gregory Peck, Jack Lemmon, Kirk Douglas, James Stewart and Katharine Hepburn were read out. The bill was passed unanimously, and the medal was presented to the Wayne family in the following year.
In a 1960 interview Wayne criticized the homosexual themes of Suddenly, Last Summer (1959) and They Came to Cordura (1959).
In December 1978, just a month before he was diagnosed with stomach cancer, he joined Bob Hope and Johnny Carson in offering his services to speak out publicly against government corruption, poverty, crime and drug abuse.
In his films Wayne often surrounded himself with a group of friends/fellow actors (often unknown names but recognized faces), such as Ward Bond, Jim Hutton, Bruce Cabot, Ben Johnson, Edward Faulkner, Jay C. Flippen, Richard Boone, Chuck Roberson and his son, Patrick Wayne.
In his later years John Wayne lived near Newport Beach, just south of Los Angeles where he had a beach house, and a yacht, The Wild Goose. His house has been torn down, but The Wild Goose sails on. It is now a tour boat offering dinner cruises to John Wayne fans young and old alike. Built from a retired Navy minesweeper, the custom interior of the yacht has polished wood almost everywhere you look. It was there that in his later years the Duke often entertained, hosting card games with his good friends Dean Martin, Sammy Davis Jr., and other big name stars of the time.
In his will were instructions that, because of his suffering from lung cancer, no film of him smoking should ever be shown again. The director of Thank You for Smoking (2005), Jason Reitman, had to petition Wayne's family in order to allow him to use a scene from Sands of Iwo Jima (1949), in which Wayne's character, Sgt. Striker, survives the battle only to be killed by a sniper after lighting a cigarette. After showing them the script and describing to them what the movie was about the family agreed to allow the scene to be shown.
In November 2003 he once again commanded a top-ten spot in the annual Harris Poll asking Americans to name their favorite movie star. No other deceased star has achieved such ranking since Harris began asking the question in 1993. In a 2001 Gallup Poll, Americans selected Wayne as their favorite movie star of all time.
In the comic "Preacher", his ghost appears in several issues, clothed in his traditional gunfighter outfit, as a mentor to the hero of the series, Jesse Custer.
In the final years of his life, with the resignation of President Richard Nixon and the end of the Vietnam War, Wayne's political beliefs appeared to have moderated. He attended the inauguration of President Jimmy Carter on 20 January 1977, and along with his fellow right-winger James Stewart he could be seen applauding Jane Fonda at AFI Life Achievement Award: A Tribute to Henry Fonda (1978) (TV). Later in 1978, Wayne uncharacteristically sided with the Democrats and President Carter against his fellow conservative Republicans over the issue of the Panama Canal, which Wayne believed belonged to the people of Panama and not the United States of America.
In the late 1970s Wayne made a series of commercials for the Great Western Savings Bank in Los Angeles. The day after the first one aired, a man walked into a GW Bank branch in West Hollywood with a suitcase, asked to see the bank manager, and when he was shown to the manager's desk, he opened up the suitcase to reveal $500,000 in cash. He said, "If your bank is good enough for John Wayne, it's good enough for me." He had just closed his business and personal accounts at a rival bank down the street and walked to the GW branch to open accounts there because John Wayne had endorsed it.
In the mid-1930s Wayne was hired by Columbia Pictures to make several westerns for its "B" unit. Columbia chief Harry Cohn, a married man, soon got the idea that Wayne had made a pass at a Columbia starlet with whom Cohn was having an affair. When he confronted Wayne about it Wayne denied it, but Cohn called up executives at other studios and told them that Wayne would show up for work drunk, was a womanizer and a troublemaker and requested that they not hire him. Wayne didn't work for several months afterward, and when he discovered what Cohn had done, he burst into Cohn's office at Columbia, grabbed him by the neck and threatened to kill him. After he cooled off he told Cohn that "as long as I live, I will never work one day for you or Columbia no matter how much you offer me." Later, after Wayne had become a major star, he received several lucrative film offers from Columbia, including the lead in The Gunfighter (1950), all of which he turned down cold. Even after Cohn died in 1958, Wayne still refused to entertain any offers whatsoever from Columbia Pictures, including several that would have paid him more than a a million dollars.
Increasingly by the early 1960s Wayne used to wear three or four-inch lifts in his shoes, a practice that mystified friends and co-stars like Bobby Darin's Capucine's and Robert Mitchum's because he stood 6'4". It was possibly due to his increasing weight, health problems, and age that he wasn't able to loom as tall without lifts.
Inducted into the Hall of Great Western Performers of the National Cowboy and Western Heritage Museum in 1974.
It was no surprise that Wayne would become such an enduring icon. By the early 1970s, his contemporaries Humphrey Bogart, Tyrone Power, Errol Flynn, Clark Gable, Spencer Tracy, Paul Muni and Gary Cooper were dead. James Cagney and Cary Grant both retired from acting at 62. The careers of other stars declined considerably - both Henry Fonda and James Stewart ended up working on television series which were canceled on them. Wayne however continued to star in movies until 1976, remaining one of the top ten stars at the US box office until 1974.
Just on his sheer popularity and his prominent political activism, the Republican party in 1968 supposedly asked him to run for President of the USA, even though he had no previous political experience. He turned them down because he did not believe America would take a movie star running for the President seriously. He did however support Ronald Reagan's campaigns for governor of California in 1966 and 1970, as well as his bid for the Republican presidential nomination in 1976.